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PTFE Media Isolation Valves

The Clippard NIV series media isolation valve is a solenoid-operated device that uses a flexible diaphragm to isolate the actuation mechanism from the fluid path. Media isolation valves are commonly used for a wide variety of applications, including those that require precise, repeatable dispensing of media for analytical instrumentation. All wetted areas of the valve are PTFE, making this series ideal for use with corrosive media.

Clippard NIV Series PTFE Isolation Valves

PTFE Isolation Valve Features:

  • Low power consumption
  • Compact, lightweight design
  • Bidirectional
  • Minimal dead volume
  • All wetted areas PTFE
  • Ideal for use with corrosive media
  • High cycle life
  • Fast response time
  • Proudly made in the U.S.A.

Valve Type: 2-Way N.C, 2-Way N.O., 3-Way Selector/Diverter
Medium: Air, water, gas or compatible fluids
Temperature Range: 0 to 158°F (70°C)
Operating Pressure: Vacuum to 30 psig
Flow: 10 to 60 l/min @ 30 psig
Max. Pressure Range: 28" Hg to 30 psig
Wattage: 1.0 to 7.2 watts
Response Time: 5 to 20 ms
Connectors: 18" wire leads
Voltage: 12 or 24 VDC
Ports: #10-32, 1/4-28 UNF or 1/8 NSPC
Mounting: #2-56, #4-40 or Manifold
Wetted Materials: PTFE, Peek available
CE, RoHS Compliant
ISO 9001 Certified

Model Power Voltage Amps
NR1 1.0 watts 12 VDC 0.08
24 VDC 0.04

NR2 1.5 watts 12 VDC 0.13
24 VDC 0.06

NR3 4.2 watts 12 VDC 0.40
24 VDC 0.18

NR4 7.2 watts 12 VDC 0.60
24 VDC 0.30

NIV Series PTFE Isolation Valves Schematics

A unique feature of the NIV series is the one-piece valve stem that functions as a sealing membrane while also supporting and centralizing the poppet in the seating area. This multifunctional diaphragm/poppet results in a simplified design with fewer parts (only two for the 2-way and three for the 3-way), longer life and minimal dead volume. Choose from four orifice sizes available as 2-way normally-closed, 2-way normally-open, or 3-way selector/diverter. Special configurations available by request.

Industries and applications that commonly use these types of valves to isolate gas or liquid include: drug dispensing, laboratory equipment, analytical, chemical analysis, sampling, life science/biotech, genetic research, gas chromatography, spectrometry, DNA synthesizing, blood analyzing, printing, diagnostic equipment, fermentation, water treatment and more.

Valve Type Orifice Ports Model Part No. Width Height
2-Way Normally-Closed 0.040" 1/4-28 UNF NR1 NR1-2 0.750" 1.155"
0.062" 1/4-28 UNF NR2 NR2-2 1.000" 1.488"
0.093" 1/4-28 UNF NR3 NR3-2 1.250" 1.863"
0.156" 1/8 NPSC NR4 NR4-2 1.500" 2.088"

2-Way Normally-Open 0.040" 1/4-28 UNF NR1 NR1O-2 0.750" 1.163"
0.062" 1/4-28 UNF NR2 NR2O-2 1.000" 1.493"
0.093" 1/4-28 UNF NR3 NR3O-2 1.250" 1.814"
0.156" 1/8 NPSC NR4 NR4O-2 1.500" 2.039"

3-Way Selector/Diverter 0.040" 1/4-28 UNF NR1 NR1-3 0.750" 1.161"
0.062" 1/4-28 UNF NR2 NR2-3 1.000" 1.492"
0.093" 1/4-28 UNF NR3 NR3-3 1.250" 1.814"
0.156" 1/8 NPSC NR4 NR4-3 1.500" 2.039"

Clippard NIV Series PTFE Gradient Mixing Valves

The gradient mixing isolation valve combines multiple solenoids into a single compact unit. The valve incorporates two, three, four or six separate sources of media into one stream that is integral to a single block. The valves have independent inlets and one common outlet or one common inlet and multiple independent outlets.

These gradient manifolds are useful for solvent selection, stream splitting, flushing and other automated applications. These valves utilize a standard 2-way, normally-closed configuration. Standard options include four different orifice sizes, available in 12 VDC or 24 VDC.

Mixing Valve Features:

  • Ideal for gradient, mixing, and diverting applications
  • Compatible with corrosive and aggressive fluids
  • Variety of multi-valve configurations
  • Flow paths may be controlled individually
  • Flow paths are all the same length
  • Equal pressure drop, response time and internal volumes

Click here to learn more about NIV series
multi-channel gradient mixing valves.


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NIV Series Solenoid-Operated PTFE Media Isolation Valves