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PTFE Media Isolation Valves

The Clippard NIV Series Media Isolation Valve is a solenoid-operated device that uses a flexible diaphragm to isolate the actuation mechanism from the fluid path. Media isolation valves are commonly used for a wide variety of applications, including those that require precise, repeatable dispensing of media for analytical instrumentation. All wetted areas of the valve are PTFE, making this series ideal for use with corrosive media.

Clippard NIV Series PTFE Isolation Valves

• Low power consumption
• Compact, lightweight design
• Bidirectional
• Minimal dead volume
• All wetted areas PTFE
• Ideal for use with corrosive media
• High cycle life
• Fast response time
• Proudly made in the U.S.A.

Valve Type: 2-Way N.C, 2-Way N.O., 3-Way Selector/Diverter
Medium: Air, water, gas, compatible fluids
Max. Temperature Range: 158°F (70°C)
Operating Pressure: Vacuum to 30 psi
Flow: 10 to 60 l/min
Max. Pressure Range: 28" Hg to 30 psi
Power Consumption: 1.0 to 7.2 watts
Response Time: 5 to 20 ms
Electrical Connections: 18" wire leads
Voltage: 12 or 24 VDC
Ports: #10-32, 1/4-28 UNF or 1/8 NSPC
Mounting: #2-56, #4-40 or Manifold
Wetted Materials: PTFE
CE, RoHS Compliant
ISO 9001:2015

Model Power Voltage Amps
NR1 1.0 watts 12 VDC 0.08
24 VDC 0.04

NR2 1.5 watts 12 VDC 0.13
24 VDC 0.06

NR3 4.2 watts 12 VDC 0.40
24 VDC 0.18

NR4 7.2 watts 12 VDC 0.60
24 VDC 0.30

NIV Series PTFE Isolation Valves Schematics

A unique feature of the NIV Series is the one-piece valve stem that functions as a sealing membrane while also supporting and centralizing the poppet in the seating area. This multifunctional poppet/diaphragm/stem results in a simplified design with fewer parts (only two for the 2-way and three for the 3-way), longer life and minimal dead volume. Choose from four orifice sizes available as 2-Way Normally-Closed, 2-Way Normally-Open, or 3-Way Selector/Diverter. Special configurations available by request.

Industries and applications that commonly use these types of valves to isolate gas or liquid include: drug dispensing, laboratory equipment, analytical, chemical analysis, sampling, life science/biotech, genetic research, gas chromatography, spectrometry, DNA synthesizing, blood analyzing, printing, diagnostic equipment, fermentation, water treatment and more.

Valve Type Orifice Ports Model Part No. Width Height
2-Way Normally-Closed 0.040" 1/4-28 UNF NR1 NR1-2 0.750" 1.155"
0.062" 1/4-28 UNF NR2 NR2-2 1.000" 1.488"
0.093" 1/4-28 UNF NR3 NR3-2 1.250" 1.863"
0.156" 1/8 NPSC NR4 NR4-2 1.500" 2.088"

2-Way Normally-Open 0.040" 1/4-28 UNF NR1 NR1O-2 0.750" 1.163"
0.062" 1/4-28 UNF NR2 NR2O-2 1.000" 1.493"
0.093" 1/4-28 UNF NR3 NR3O-2 1.250" 1.814"
0.156" 1/8 NPSC NR4 NR4O-2 1.500" 2.039"

3-Way Selector/Diverter 0.040" 1/4-28 UNF NR1 NR1-3 0.750" 1.161"
0.062" 1/4-28 UNF NR2 NR2-3 1.000" 1.492"
0.093" 1/4-28 UNF NR3 NR3-3 1.250" 1.814"
0.156" 1/8 NPSC NR4 NR4-3 1.500" 2.039"

Clippard NIV Series PTFE Gradient Mixing Valves

NIV series mixing valves feature multiple solenoids connected around a central body. This unique design provides significant reduction in internal volume with enhanced mixing capabilities. Each actuator operates independently, allowing for flow of various media to be mixed or for one media to be split into multiple streams.

These valves utilize a standard 2-way, normally-closed configuration. Standard options include four different orifice sizes, available in 12 VDC or 24 VDC.


• Ideal for gradient, mixing, and diverting applications
• Compatible with corrosive fluids
• Variety of multi-valve configurations

Available with two, three, four, and six valves, these units provide a compact solution for applications requiring an inert wetted path for corrosive or aggressive liquids. Special configurations available by request.

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